Nail-unit biopsy
ListedA specialist determines how to obtain a diagnostic sample; cosmetics or antifungals must not delay assessment.
Melanoma of the nail unit is a potentially serious cancer that may resemble a bruise. A collection of blood beneath a nail after injury or repeated pressure.


The same eight facts on every condition comparison.

Subungual Melanoma A broad brown-black stripe extends lengthwise through the nail.

Subungual Hematoma A purple-black patch is visible under part of the large toenail.
Malignant pigment cells multiply within the nail unit. Their growth can affect the nail plate, nearby tissue or the pigment visible through the nail.
Impact or repeated pressure damages small blood vessels beneath the nail. Blood collects between the nail plate and its bed, creating a dark patch that can be painful.
Subungual Melanoma. Usually diagnosed in adults, but an unexplained changing nail lesion needs assessment at any age.
Subungual Hematoma. Can occur at any age after injury.
Malignant pigment cells grow within the nail unit.
Impact, pressure or repetitive injury damages the nail unit.
Evidence labels come from each condition’s own treatment list.
Protect a mildly injured nail and use suitable pain relief if needed. Severe pressure pain, a crush injury or an open wound may need prompt professional assessment; do not drill or burn a hole in the nail yourself.
A specialist determines how to obtain a diagnostic sample; cosmetics or antifungals must not delay assessment.
The outlook depends on the cancer's thickness and stage when diagnosed. Prompt assessment and appropriate treatment matter; an unexplained changing nail band should not be watched indefinitely as a presumed bruise.
The dark area should gradually move toward the nail tip as the nail grows. This takes months and is slower in toenails; unexplained pigment or pigment that does not grow out needs assessment.
It can invade and spread; early biopsy-based diagnosis is important.
A significant injury may include a fracture or nail-bed wound.
Seek prompt specialist assessment for a changing dark nail band, pigment spreading onto skin, bleeding or unexplained nail destruction.
Get care for severe pain, a crush injury, an open wound or unexplained pigment that does not move with nail growth.
Melanoma of the nail unit is a potentially serious cancer that may resemble a bruise.
Photograph changes and arrange examination. Do not rely on a remembered injury to exclude melanoma.
Seek prompt specialist assessment for a changing dark nail band, pigment spreading onto skin, bleeding or unexplained nail destruction.
A collection of blood beneath a nail after injury or repeated pressure.
Protect the nail, use roomy footwear and do not drill or burn a hole in it yourself.
Get care for severe pain, a crush injury, an open wound or unexplained pigment that does not move with nail growth.
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