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Impetigo vs Molluscum

Impetigo is a bacterial skin infection that weeps and crusts. The sores are wet, and they dry into a golden-yellow crust that looks like dried honey. Molluscum is a viral infection that makes firm, dry bumps. They are smooth and pearly, with a small dimple on top, and they do not ooze. Impetigo spreads over days and is treated with an antibiotic. Molluscum sits for months and often needs nothing.

Last Updated: October 15, 2026

At a glance

The differenceImpetigoMolluscum Contagiosum
What is it?Bacteria growing in the top layerA poxvirus in the top layer
What they look likeWet sores with a honey-gold crustSmooth, pearly, with a centre dimple
How treatment differsAntibiotic cream or tabletsUsually left to clear

Impetigo

Impetigo vs Molluscum — illustration

Molluscum Contagiosum

Impetigo vs Molluscum — illustration

What is it?

Impetigo

Bacteria growing in the top layer

Group A streptococcus or staph bacteria get through a small break in the skin — a scratch, a bite, a patch of eczema — and multiply in the surface layer.

Molluscum Contagiosum

A poxvirus in the top layer

A virus from the pox family infects skin cells and fills each bump with a soft white core. Nothing is infected below the surface.

What they look like

Impetigo

Wet sores with a honey-gold crust

It starts as a small red patch or blister, breaks open, weeps, and dries into a thick yellow crust. Lift a crust and the skin underneath is raw and moist.

Molluscum Contagiosum

Smooth, pearly, with a centre dimple

Firm, dome-shaped and dry, skin-coloured or slightly pink. The small pit in the middle is the most useful sign.

Different Skin Tones

Impetigo

Molluscum Contagiosum

Where they appear

Impetigo

Around the nose and mouth

Classically the face, especially near the nostrils and lips, then the hands, arms and anywhere skin is already broken.

The classic place, because the bacteria are carried in the nose and fingers do the rest. Honey-colored crust around the nostrils and the mouth in a child is the picture most people know.

Impetigo starts wherever the skin was already open, so it can turn up anywhere: a scratched bite, a graze, a patch of eczema. Hands, arms and lower legs come next after the face. The blistering form is more often on the trunk, in skin folds and around the nappy area in babies.

Molluscum Contagiosum

Trunk, armpits and skin folds

Chest, tummy, sides, armpits, the crooks of the elbows and the backs of the knees.

In children the usual places are the trunk, the armpits, the inner arms, the neck and the face — skin that is warm, folded and rubbing. Wherever they are, they cluster in creases and run in lines where a child has scratched and carried the virus along.

In adults, bumps on the lower abdomen, the groin, the inner thighs and the genitals usually mean the virus was passed on through sexual contact, and testing for other infections is normally offered at the same time.

What’s happening in the skin

Impetigo

Healthy skin is a sealed sheet. Bacteria live on top of it all the time and cause no trouble while it stays closed.

A scratch, an insect bite, a cold sore or a patch of eczema opens the surface. The break is often too small to notice.

Staph or strep bacteria that were already sitting on the skin move into the opening. Impetigo is ordinary bacteria in the wrong place, not a sign of dirty skin.

The area turns red and sore as the immune system arrives. Small blisters form just under the top layer, and they break easily.

Fluid from the broken blisters dries into a gold, honey-colored crust. That crust is full of bacteria, which is how it spreads to other spots and to other people.

Molluscum Contagiosum

The barrier is intact and nothing is getting through it.

A poxvirus, spread by skin-to-skin contact and by shared towels, mats and baths. Damp or eczema-prone skin lets it in more easily.

The virus makes skin cells multiply into small firm domes with a dimple in the middle, each one full of virus.

Scratching or shaving over a bump carries the virus along the line of the scratch, which is why new ones appear in rows.

Eventually it recognizes the infection and clears it, often with a red, sore-looking flare first. That flare is the sign it is ending, not worsening.

Symptoms

Impetigo

Itchy, and a bit sore

Scratching is how it moves to new skin, which is why the sores often appear in a line or a cluster.

Molluscum Contagiosum

Usually neither

Some bumps itch. A scratched one turns red and sore, and that red ring often means it is about to clear.

How it changes over time

Impetigo

Days, and it spreads fast

Untreated, it keeps opening new sores and can stay contagious for weeks. With an antibiotic it usually settles within about a week.

Molluscum Contagiosum

Months, and it spreads slowly

Bumps clear on their own in about 6 to 18 months. New ones keep arriving while old ones fade, so the crop looks endless for a while.

When to get medical help

Impetigo

Almost always worth a visit

Impetigo does not reliably clear on its own, and treatment shortens it and stops it spreading to others.

Molluscum Contagiosum

Only if something changes

Worth a visit if bumps are near the eyelid, if one becomes hot and swollen with spreading redness, or if the diagnosis is not clear.

How treatment differs

Impetigo

Antibiotic cream or tablets

An antibiotic ointment such as mupirocin or fusidic acid for a small patch. Tablets when it is widespread. It stops being contagious about a day after treatment starts.

Molluscum Contagiosum

Usually left to clear

Most children are left alone, because the bumps go anyway and the treatments can sting or mark the skin. Single bothersome bumps can be scraped or frozen.

Questions Patients Ask

How do I tell impetigo from molluscum at a glance?

Impetigo is wet and crusted. Molluscum is dry and firm. A golden-yellow crust that looks like dried honey is impetigo; a smooth pearly bump with a dimple in the middle is molluscum.

Does molluscum need antibiotics?

No. It is a virus, so antibiotics do nothing to it. They are only used if one bump has become infected with bacteria on top.

Which one spreads faster?

Impetigo. It can double in a few days, while molluscum drifts along for months. Impetigo also stops being contagious quickly once treatment starts.

Can a child have both at once?

Yes, and it is common. Scratching a molluscum bump breaks the skin, and broken skin is how impetigo bacteria get in.

When can my child go back to school?

With impetigo, usually about 24 hours after antibiotic treatment starts, or once the sores have dried and crusted. Molluscum is not a reason to stay home at all.

Will either one leave a scar?

Impetigo usually heals without a scar, though it can leave a pale or darker mark for a few months. Molluscum can leave a small mark, more often from scratching or from treatment than from the bump itself.