PROCEDURE

Radiesse

An injectable made of calcium-based microspheres in a gel. It adds volume the day it is placed and then prompts the skin to build collagen. It cannot be dissolved.

Reviewed by Dr. Schwarz, Board-Certified Dermatologist
Last updated: 10/22/2026
Volume and contourInjectable

Key facts

Treats

Selected volume loss or contour concerns

Recovery

Swelling or bruising for days

Treatment plan

Often 1–2 sessions; later maintenance

Typical cost

Per-syringe quote

What is it?

It is a calcium-based filler.

Radiesse contains calcium hydroxylapatite microspheres in a gel.

It provides structure.

It supports tissue and triggers a later tissue response.

Diluted uses differ.

Hyperdilute use is not the same as volumizing.

Ask about the plan.

The intended use determines the evidence and rescue options.

What it treats

Volume Loss on light skin.
Strong evidence

Volume Loss

Restores fullness.

Sagging Skin on light skin.
Moderate evidence

Sagging Skin

Diluted versions improve firmness.

A relaxed forehead with pronounced deep horizontal furrows.
Moderate evidence

Deep Wrinkles

Fills deep folds.

A relaxed forehead with faint shallow horizontal fine lines.
Little evidence

Wrinkles and Fine Lines

Too heavy for fine lines.

Thin Lips on light skin.
Not effective

Thin Lips

Not used in the lips.

Treatment areas

Treatment areas
Map options
Areas treated

Radiesse

Commonly treated areas

Facial volume loss and backs of the hands; product use and dilution depend on the plan.

Skin tones

Lighter skin

Low risk

Bruising fades in a week.

Medium skin

Low risk

Not a pigment-based treatment.

Deeper skin

Low risk

Bruising may leave brief dark marks.

How it works

Radiesse mechanism diagram. The material is placed: A clinician injects calcium hydroxylapatite in a gel carrier. The gel provides initial support: Early correction depends on formulation and placement. Collagen response develops: Tissue remodeling contributes as the gel carrier is absorbed.
Diagram explanation

The material is placed: A clinician injects calcium hydroxylapatite in a gel carrier. The gel provides initial support: Early correction depends on formulation and placement. Collagen response develops: Tissue remodeling contributes as the gel carrier is absorbed.

Schematic illustration. Technique and response vary. This explains a mechanism and does not specify treatment settings.

Before your treatment

2–4 weeks before

2 weeks before: Events and dental: Do not book within two weeks of an event; bruising and swelling are normal, and swelling makes the early result look bigger.

Before you book: Infections and scans: Reschedule if there is an active infection, cold sore or inflamed cyst in the area.

The week before

A few days before: Blood thinners: Ask the prescribing doctor before pausing one.

The day before: Alcohol: None.

Day of treatment

Arrival & prep

The area is assessed sitting up, photographed, and the injection points marked.

Treatment

The product goes in deep, often onto or just above bone, through a needle or a blunt cannula, then each area is molded smooth.

A face takes about 20 to 40 minutes; hands and diluted treatments are quicker. You feel pressure and a deep ache more than sharp pain, with stinging at the entry points.

Before you leave

Swollen, with small red marks at the entry points and possible bruising.

After your treatment

First 24 hours

Days 1 to 3: Bruises appear at needle sites and the area feels tender and firm — swelling and product, not a lump.

Days 2–7

Days 4 to 14: Swelling drains and the area softens.

Weeks 2–4

Weeks 2 to 12: The gel carrier is absorbed while new collagen replaces it.

Time to results

Immediately

How long results last

About 12–18 months

Risks

Most reactions are injection-site effects that settle within a week or two

swelling, bruising, redness and firmness. The risks specific to this product come from its firmness and the fact that it cannot be dissolved.

A lump you can feel

Nodules are more likely in mobile areas and where product sat too shallow. Some settle; others need steroid injection, massage under local anesthetic, or occasionally minor surgery. Raise it early.

A pale or white line under the skin

Product too close to the surface can show through on thin skin. Report it rather than waiting it out.

Spreading redness or tenderness

This can mean infection around the injected material and usually needs antibiotics.

A new lump months later

A delayed inflammatory reaction is uncommon but recognized, and treatable.

Unevenness between the two sides

Say so at the review appointment, while a plan can still be made.

Cost

Typical cost

Per syringe, similar to HA filler

Pricing

In the US a syringe usually runs about $700 to $1,200.

Insurance

Insurance does not cover cosmetic use.

Alternatives

Editorial illustration for Dermal Fillers, based on the entry’s treatment or equipment reference.
If reversibility matters

Hyaluronic acid fillers

Softer, usable in lips and under the eyes, and reversible with hyaluronidase. Radiesse is firmer and lasts longer in some areas, but a poor result cannot be undone.

Editorial illustration for Sculptra, based on the entry’s treatment or equipment reference.
If reversibility matters

Sculptra

Moderate to strong evidence. A pure collagen stimulator with no same-day change, given as a course, and typically lasting around two years. Broader and softer in effect, and also not reversible.

Editorial illustration for Fat transfer, based on the entry’s treatment or equipment reference.
If you want another option

Fat transfer

Surgical, done once, potentially long-lasting, with real downtime and a variable amount of fat surviving.

Representative skin-treatment handpiece and coupling gel, not a specific radiofrequency or ultrasound model.
If you want another option

Energy tightening devices

Radiofrequency and ultrasound firm the skin rather than support it. Useful when the problem is laxity rather than lost volume, with modest results over several sessions.

Representative capped cosmetic injectable syringe, not a particular filler or formulation.
If you prefer a similar option

Skin boosters and microneedling

Similar aims for skin quality on the neck, chest and hands, with different downtime and different costs.

Tretinoin — Header Image
If lines are your concern

Topical retinoid

The one home product with solid evidence for building collagen. It improves skin quality and fine lines. It does not restore support or shape a jawline.

Existing daily sunscreen illustration.
If sun protection is the goal

Daily sunscreen

Prevents further collagen loss, which is the thing this treatment is compensating for.

Illustration: Generic topical cream tube and white cream.
If you prefer home care

Firming creams marketed for the jawline or neck

Some improve surface texture and hydration. None move the underlying structure.

Questions

Is Radiesse a filler or a collagen stimulator?

Both. The gel gives volume the day it is injected, and the calcium particles prompt new collagen over the following months as the gel is absorbed.

Can Radiesse be dissolved?

No. Hyaluronidase dissolves hyaluronic acid only, and there is no equivalent here. A result you dislike has to be managed with time, massage, steroid injection or, rarely, minor surgery. Understand that before you agree to it.

How long does it last?

Usually about 12 to 18 months in the face, then a gradual decline. Some people keep a little extra firmness from the collagen that formed, but that is a bonus, not the plan.

Why can it not go in my lips?

It is firm and lips move constantly. That gives a high rate of lumps, and a lump in a lip is visible and hard to treat in a product that cannot be dissolved. Hyaluronic acid is used there instead.

Will it show up on an X-ray or a dental scan?

Yes, on X-rays and CT scans, which is harmless. Tell your dentist and any radiologist so a bright patch is not investigated as something else.

Will it feel hard?

It should not, once swelling settles. Placed deep, it feels like your own tissue. Firmness you can feel through the skin after a few weeks usually means it sat too shallow — worth reporting.

Dermapedia on YouTube