CONDITION

Shingles

Shingles is a painful, blistering rash that follows one nerve on one side of the body. It is caused by the chickenpox virus waking up years later. Antiviral tablets help most when they are started within three days of the rash appearing.

Updated 10/22/2026
Viral infectionPainful rash

Key facts

Shingles at a glance.

Typical signs

Painful blisters in a stripe

Common locations

One side of the body

Expected course

Skin heals in 2–4 weeks

Treatment options

Early antivirals and pain relief

What is it?

Top things to know about Shingles

  1. It is a reactivated virus. The chickenpox virus can lie dormant in nerves and later reactivate.
  2. It follows a nerve. Inflammation follows a nerve band and causes a skin eruption.
  3. Risk rises with weaker immunity. Age and immune-lowering treatment increase risk, but younger people can get it.
  4. Care has several parts. Antivirals, pain control and checking for complications are each addressed.

What it looks like

What Shingles looks like

Shingles is a reactivation of the chickenpox virus. It usually starts with burning, tingling or pain on one side of the body, followed a few days later by a band or strip of red skin with clusters of fluid-filled blisters. The rash follows the path of one nerve and does not cross the midline. Blisters crust over in 7 to 10 days. Shingles near the eye needs urgent medical care.

Shingles is usually described by where it appears.

Where it shows up

The marked band is one possible trunk location. Shingles usually affects one side in a nerve distribution; other sites, including the face, are possible.

Trunk

Locations on the front of the trunk.

On different skin tones

Shingles on different skin tones

On lighter skin, the shingles rash looks red with clear blisters. On brown and Black skin, the skin around the blisters may look dark brown, purple or gray instead of red. Healing can leave dark or light spots that last for months. The one-sided band pattern is the most reliable clue on every skin tone.

What happens in Shingles?

Shingles mechanism diagram. Painful blisters can appear: The rash often follows a one-sided nerve area. Reactivation follows a nerve: The virus travels toward the skin. The virus rests in a nerve ganglion: Varicella-zoster stays after chickenpox.

Varicella-zoster virus remains dormant in sensory nerves after chickenpox. When it reactivates, it travels toward the skin and can cause pain and grouped blisters in a one-sided nerve distribution.

  1. Painful blisters can appear: The rash often follows a one-sided nerve area.
  2. Reactivation follows a nerve: The virus travels toward the skin.
  3. The virus rests in a nerve ganglion: Varicella-zoster stays after chickenpox.

Causes and triggers

What causes Shingles

Causes

Why it happens

Shingles is caused by the chickenpox virus waking up years after it first infected you. The virus stays dormant in nerves and can reactivate later.

Risk factors

Raise the odds

  • Age over 50
  • Weakened immunity
  • Cancer treatment
  • Never vaccinated

Triggers

Bring it on or make it worse

  • Weakened immunity (Well established)
  • Immune-suppressing medicines (Well established)
  • Illness (Strong link)
  • Stress (Possible)

When it usually starts

When it usually starts

Shingles

Risk rises with age, particularly after age 50, but younger people can be affected.

Daily care

Daily care for Shingles

Habits that help

Keeping the rash covered

A loose, non-adhesive dressing until it crusts.

Loose cotton clothing

Less pressure over the band, less pain.

Plain petrolatum on broken areas

Stops cracking and lowers infection risk.

Rest, and lowering expectations

Pushing through shingles is not rewarded.

The shingles vaccine

Two doses, more than 90 percent effective after 50.

Getting vaccinated after an episode

One episode does not protect you.

Seek early treatment for suspected shingles, ideally within 72 hours

Early treatment is most effective. Eye involvement, immune suppression or new lesions can warrant treatment even after 72 hours; do not assume it is too late to seek care.

Discuss how age affects monitoring and recovery

Longer episodes and more lasting nerve pain.

Discuss immune suppression and the need for earlier assessment

Raises reactivation, spread and complications.

Habits to avoid

Avoid: Breaking or scratching the blisters

Spreads virus and turns marks into scars.

Avoid: Ignoring a rash near the eye

Forehead, eyelid or nose blisters, same day.

Avoid: Ear blisters with facial weakness

Droop, hearing change or dizziness is urgent.

Avoid: Not covering the rash

Blister fluid gives chickenpox to anyone not immune.

Avoid: Tight clothing and adhesive dressings

Pressure worsens pain and tears blisters.

Avoid: Poor sleep during the episode

Pain and sleep loss feed each other.

Avoid: Waiting to see if it settles

Antivirals work best within 72 hours.

Avoid: Leaving severe pain untreated

Linked with worse nerve pain later.

Avoid: Topical antiviral cream

Antiviral creams sold for cold sores do not work for shingles. The virus is in the nerve, not just on the surface, so treatment has to be swallowed or given by drip. Reaching for a cream instead is one of the ways the 72-hour window gets missed.

Treatments

Treatments for Shingles

Existing Dermapedia illustration of acetaminophen and ibuprofen.
Limited evidence

Acetaminophen and ibuprofen

The first step for shingles pain, and enough on their own for a milder episode. They work better taken regularly than only when the pain peaks. Shingles pain is nerve pain, so if these are not holding it, that is a reason to ring your doctor rather than to take more.

Existing Dermapedia illustration of calamine lotion.
Limited evidence

Calamine lotion

Dabbed on while the blisters are present, it cools the skin and takes the edge off the itching. A cool compress does much the same thing. Neither shortens the episode, and neither should be rubbed in, because breaking the blisters spreads virus and can leave scars.

Five colloidal oatmeal eczema products lined up on white: tubes, a jar and a pump lotion
Limited evidence

Colloidal Oatmeal

An oatmeal soak can settle itching while the rash is blistering, in cool rather than hot water. It is comfort only. It does not change how long shingles lasts or whether nerve pain follows.

Existing educational treatment illustration: Petrolatum

Petrolatum

A thin layer of plain petroleum jelly on broken or crusting areas stops them drying and cracking, which lowers the risk of bacteria getting in. It has no effect on the virus itself. Use it under a loose, non-stick dressing rather than an adhesive one, which tears blisters when it comes off.

Outlook

What to expect with Shingles

An episode runs two to four weeks, the pain sometimes longer. Most people get it once, though it can recur if the immune system is suppressed.

  1. 1

    Before the rash · Days 1 to 5

    Burning, stabbing, aching, itching or extreme sensitivity in one area on one side, with nothing to see. Some people also feel unwell.

  2. 2

    Rash appearing · Days 1 to 3 of the rash

    Pink, red or darker patches appear in a band, then small blisters cluster on them. New blisters can keep coming for about five days.

  3. 3

    Blistering · Days 3 to 7

    The blisters fill, some turn cloudy, and they may join up. The fluid is contagious to anyone who has never had chickenpox.

  4. 4

    Crusting · Days 7 to 10

    The blisters dry and crust. Once everything has crusted, the rash is no longer contagious.

  5. 5

    Clearing · Weeks 2 to 4

    Crusts fall away, leaving pink skin, or brown to gray on deeper skin tones. Deep blisters can scar permanently. In some people, mostly older adults, nerve pain continues after the skin heals - postherpetic neuralgia. It can last months, and it is why early antivirals and pain control matter.

Complications

Complications to know about

Postherpetic neuralgia

Nerve pain that carries on after the skin has healed, because the virus damaged the nerve it traveled down. It is the most common complication of shingles, and the risk climbs steeply with age. Starting antiviral tablets within 72 hours and controlling the pain properly from day one both lower the chance of it. It is treatable, so it is worth going back rather than waiting for it to fade.

Shingles in the eye

When the affected nerve serves the forehead and eye, blisters appear on the forehead, the eyelid or the tip and side of the nose, and the eye itself can be involved. It can cause lasting damage to sight. Blisters anywhere in this area are a same-day problem, and often need an eye specialist as well as antiviral tablets.

Shingles in the ear

Blisters in or around one ear, together with weakness on that side of the face, and sometimes a change in hearing, ringing or dizziness. It is uncommon. It needs urgent treatment, because the facial nerve recovers better the sooner antiviral tablets and steroids are started.

When to get help

When to get help

When to seek care

Seek prompt care when shingles is suspected because antivirals work best early. Eye or ear involvement, widespread blisters or weakened immunity needs urgent assessment.

Questions

Questions you might be asking.

Am I contagious?

Not with shingles - nobody catches shingles from you. But the blister fluid can give chickenpox to someone who has never had chickenpox and never been vaccinated. Keep the rash covered, wash your hands, and stay away from newborns, pregnant people who are not immune, and anyone immunosuppressed until it crusts.

Is it too late for antivirals if I am past 72 hours?

Possibly not. The evidence is strongest inside 72 hours, but treatment is often still given if new blisters are forming, if you are older, if the rash involves the face or eye, or if you are immunosuppressed. Being late is a reason to be seen today.

What is postherpetic neuralgia?

Nerve pain that continues after the rash heals, from damage to the nerve the virus traveled down. Much more common in older adults, and it can last months. It is treatable with different drugs from ordinary painkillers, so go back rather than waiting it out.

Should I get the vaccine if I have already had shingles?

Generally yes. One episode does not protect you from another, and vaccination is recommended once an episode has cleared. Ask your doctor about timing.

Why is it only on one side?

The virus travels down a single sensory nerve, and each nerve supplies a strip of skin on one side. That is also why the rash stops abruptly at the midline - one of the clearest clues.

Can I get it more than once?

Yes, though most people do not. Recurrence is more likely if your immune system is suppressed. If it has happened more than once, ask whether anything underlying should be looked into.

Sources

Sources and further reading

Dermapedia on YouTube