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Most people who reach me with hidradenitis suppurativa have been told for years that they get boils — cut and drained, course after course of antibiotics, and more than one question about how they wash. This has nothing to do with hygiene. The delay is the real problem, because it commonly takes years to get the name and those are the years the tunnels and scars that are hardest to treat are forming, so if a painful lump has come back in the same fold more than twice, get a proper appointment. It is treatable — not curable, but treatable — and the options run well past antibiotics to hormonal treatment, biologic injections and small procedures that permanently remove a tunnel.
— Dr. Schwarz, Board Certified Dermatologist
Key Facts
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| How common | Around one in a hundred people, though it is heavily under-diagnosed and often goes years without a name |
| Who gets it | Usually starts after puberty, most often between the late teens and the thirties. More common in women, and in people with a family history |
| Curable or managed | Managed. Early disease can be controlled well with medication; established tunnels and scars need a procedure to remove |
| Prescription needed | Yes, for anything beyond an antiseptic wash |
| Time to improve | Weeks to a few months for most medications. A single flare settles over days |
What It Is
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Hidradenitis suppurativa is an inflammatory condition of the hair follicle, not the sweat glands, despite the name. It affects skin that folds and rubs — the armpits, groin, buttocks, inner thighs, and under the breasts. It is sometimes called acne inversa, because it behaves like severe acne in the wrong places.
It takes a few forms, usually in the same person over time. Deep painful lumps that feel like a marble under the skin and last days to weeks. Abscesses that swell, burst and drain fluid with a strong smell. Blackheads appearing in pairs, side by side, which is specific to this condition. And, over years, sinus tracts — tunnels running under the skin between lumps, draining on and off and never closing.
Doctors stage it with Hurley stages. Stage one is lumps and abscesses with no tunnels. Stage two is tunnels and scarring in separate patches with normal skin between. Stage three is widespread tunnels across a whole area. Staging sets the treatment — stages one and two are largely medical, stage three usually needs surgery as well.
What it is not matters as much. Not contagious, not a sexually transmitted infection, not a hygiene problem, and not primarily bacterial — swabs are often negative or grow ordinary skin bacteria. The pus is the immune system responding to a follicle that burst under the skin, not proof of an infection antibiotics will cure.
Symptoms
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Early Nodules
Abscesses and Draining
Tunnels and Scarring
How It Looks by Skin Tone
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Hidradenitis suppurativa is more common in Black patients in the data we have, and it is diagnosed later in that same group.
Part of the delay is what inflammation looks like. The angry red of a flare reads as brown, purple or simply darker on deeper skin tones, so a genuinely inflamed lump gets judged mild and sent away with a wash. Pain, swelling and recurrence in the same fold are the reliable signals and should outweigh color. What is left behind differs too. On deeper skin tones healed lesions leave flat dark marks that take many months to fade, and the raised scars this condition produces are more likely to turn thick or keloid. Both argue for treating sooner and choosing procedures carefully — deroofing a tunnel, which removes its roof rather than cutting out a wide block of skin, generally leaves a better result. Laser hair removal can reduce flares by taking the follicle out of the picture, but the wrong laser on deeper skin tones causes burns and pigment change. The long-pulsed Nd:YAG laser is usually the choice. Ask which device will be used and what experience the clinic has with your skin tone.
Where It Shows Up
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What Happens in the Skin
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This is what is going wrong under the skin, in the order it happens. Click a step to see it.
How Hidradenitis Suppurativa happens
Skin basics
In the armpits, groin and under the breasts, hair follicles sit in warm skin that folds and rubs. When one is working normally, the keratin its lining sheds travels up and out through the open pore, and the oil and skin bacteria go with it. Everything ends up above the surface.
A hair follicle in a fold fills with keratin, the protein that makes up the outer layer of skin, and the opening blocks. This is why friction, shaving and heat set flares off, and why the condition sits in folds rather than anywhere else.
The blocked follicle keeps filling from below, swells, and gives way sideways into the deeper tissue instead of opening at the surface. That is the moment a lump becomes painful, and it is why squeezing it makes things worse rather than better.
Keratin, oil and ordinary skin bacteria are now deep in tissue where they do not belong, and the immune system reacts hard. That reaction is the pain, the swelling and the pus, and it is why anti-inflammatory treatment works better here than antibiotics used to kill an infection.
When the same area goes through this cycle again and again, the body walls it off with tunnels lined by skin cells, and thick rope-like scars form around them. Tunnels do not close on their own and medication cannot shut them. Almost everything on the lists below is pushing on this step.
The outer film of dead cells and oil. It holds water in and keeps irritants out, and it is thinner than a sheet of paper. Almost every dry, itchy, stinging skin problem starts here.
The outer layer, and the only one anything in a jar reaches. It renews itself constantly: a cell made at the bottom takes about a month to reach the surface and flake off. Most of what a skincare product does, it does here.
The living layer underneath, holding the blood vessels, the nerves and the collagen. It is where lasting change happens and it is hard to reach: most of what is sold for the skin never gets this far.
The lumps form in four steps.
A hair follicle in a fold plugs with keratin, the protein in the outer layer of skin. It keeps filling from below, swells, and bursts sideways under the skin instead of out through the surface. The immune system meets that spilled material — keratin, oil, bacteria that normally live harmlessly on skin — deep in tissue where it does not belong, and reacts hard. That reaction is the pain, the swelling and the pus. When the same area cycles through this over and over, the body walls it off with tunnels lined by skin cells, and those tunnels do not close.
Why it happens to some people is only partly understood. Genetics matter, and a substantial share of patients have a relative with it. So do hormones, since it starts after puberty, often flares before periods, and frequently settles after menopause. Smoking and excess weight make it considerably worse, though plenty of people with the condition have neither. The underlying problem is an overactive immune response in the skin, which is why medicines that damp that response down work better than antibiotics used as antibiotics.
Risk Factors
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None of these cause hidradenitis suppurativa on their own, and having all of them does not mean you will get it. They raise the odds or worsen an existing case.
Course
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It runs in flares and quiet periods, and follows a longer arc over years. Not everyone progresses. The toll is real — pain, drainage, dressings, clothes chosen around it, embarrassment about the smell — and rates of depression and anxiety are high, worth raising at an appointment.
A single painful lump appears in one armpit or the groin. It is drained or given antibiotics, and settles.
The lump returns in the same place. That repeat is the condition announcing itself, and where it should be named. In practice it takes years and several doctors.
A flare builds over a few days and hurts most just before it bursts or is drained. Frequency varies enormously, and for many they cluster before periods.
More sites get involved, single lumps join into tunnels, and tunnels heal into thick rope-like scars that can restrict how an arm or leg moves. This is why you treat early rather than ride out each flare.
Stopping smoking, losing weight where that applies, and proper medical treatment all reduce severity. Tunnels removed surgically do not come back, which makes surgery worth considering rather than a last resort.
What Makes It Better & Worse
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It is not one problem, it is four — a follicle plugs, it bursts under the skin, the immune system reacts to what spilled, and repeated cycles leave tunnels and scars. What acts on step four causes permanent change, so address it first even when a flare feels more urgent.
What is driving yours?
A hair follicle in a fold fills with keratin, the protein that makes up the outer layer of skin, and the opening blocks. This is why friction, shaving and heat set flares off, and why the condition sits in folds rather than anywhere else.
The blocked follicle keeps filling from below, swells, and gives way sideways into the deeper tissue instead of opening at the surface. That is the moment a lump becomes painful, and it is why squeezing it makes things worse rather than better.
Keratin, oil and ordinary skin bacteria are now deep in tissue where they do not belong, and the immune system reacts hard. That reaction is the pain, the swelling and the pus, and it is why anti-inflammatory treatment works better here than antibiotics used to kill an infection.
When the same area goes through this cycle again and again, the body walls it off with tunnels lined by skin cells, and thick rope-like scars form around them. Tunnels do not close on their own and medication cannot shut them. Almost everything on the lists below is pushing on this step.
What helps
- Stopping smoking The highest-value change available.
- An antiseptic wash Benzoyl peroxide or chlorhexidine a few times a week.
- Hormonal treatment Spironolactone or a combined pill, where flares track the cycle.
- Metformin Added where there is insulin resistance or polycystic ovary syndrome.
- Loose breathable clothing Cotton, no waistband over a fold, damp clothes changed promptly.
- Laser hair removal Removing the hair removes the follicle that plugs.
- Weight loss where it applies Less friction, less background inflammation.
What makes it worse
- Smoking The clearest avoidable factor, and it acts on the disease itself.
- Friction and tight clothing Waistbands, seams, tight jeans and underwire set flares off.
- Shaving and waxing the area Both irritate the follicle and cause ingrowns.
- Heat and trapped sweat Hot weather, and damp gym gear left on.
- Excess weight More friction, more affected folds, more background inflammation.
- Hormonal shifts Many people flare reliably the week before a period.
- Deodorants and antiperspirants Fragrance or alcohol on inflamed skin irritates.
What makes it worse
- Squeezing or lancing at home Pushes the contents sideways and helps a tunnel form.
What helps
- Topical clindamycin An antibiotic lotion for mild disease, with benzoyl peroxide.
- Oral tetracycline antibiotics Doxycycline or lymecycline, for the anti-inflammatory effect.
- Clindamycin with rifampicin Two antibiotics together for moderate disease.
- Biologic injections Adalimumab and secukinumab act on the driving immune signals.
- A steroid injection into a lump Settles one painful flare within a day or two.
- Warm compresses Ease pain and help a lump come to a head.
What makes it worse
- Stress and poor sleep Both raise background inflammation.
- Stopping treatment when it works Control is maintenance. Flares return within weeks to months.
What helps
- Deroofing Removes a tunnel's roof. It does not come back.
- Wide excision Removing a whole affected area, for advanced disease.
- Absorbent dressings Not treatment, but the right dressing changes daily life.
What makes it worse
- Waiting it out Every untreated year is more chance of tunnels.
How These Treatments Work
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Treatments for Hidradenitis Suppurativa do not all work in the same place. Tap one to see where it acts.
Pick a treatment
Skin basics
Bacteria are not the cause, but they drive the flares and the smell.
Blocks the immune messages driving the lumps and tunnels, from the inside.
Works upstream, on the hormone signal feeding the follicle.
Once tunnels have formed under the skin, no drug closes them.
These do not cause it, but they decide how often it flares.
The outer film of dead cells and oil. It holds water in and keeps irritants out, and it is thinner than a sheet of paper. Almost every dry, itchy, stinging skin problem starts here.
The outer layer, and the only one anything in a jar reaches. It renews itself constantly: a cell made at the bottom takes about a month to reach the surface and flake off. Most of what a skincare product does, it does here.
The living layer underneath, holding the blood vessels, the nerves and the collagen. It is where lasting change happens and it is hard to reach: most of what is sold for the skin never gets this far.
Over-the-Counter Products
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Everything here you can buy without seeing anyone.





No over-the-counter options listed yet.
Prescriptions
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These need a prescription.


















No prescription treatments listed yet.
Procedures
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These are done in the office, usually over several visits.





No procedures listed yet.
When to See a Dermatologist
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Push for this far sooner than most people come in, because how early it is treated is the best predictor of how it turns out, and most people wait years for the name. Book if a painful lump has come back in the same armpit, groin, buttock or under-breast fold more than twice, if lumps drain or smell, if you can feel a firm cord or tunnel between two spots, if scars are forming, if repeated antibiotic courses give no lasting improvement, or if pain or dressings are affecting work, sleep or relationships. Ask for a dermatology referral and use the name, because it is diagnosed on the pattern rather than a test, and get urgent care if a flare comes with fever, spreading redness or feeling unwell, or if pain stops you moving the limb or sitting down. No blood test, scan or swab diagnoses this — it is the right lesions, in the right places, coming back two or more times in six months — and you should leave with a name, a stage and a plan that is not another course of antibiotics.
— Dr. Schwarz, Board Certified Dermatologist
Complications
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Scarring and restricted movement
Depression and anxiety
Squamous Cell Carcinoma
Lookalikes
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Folliculitis
Epidermal Inclusion Cyst
Ingrown Hairs
Myths
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- "It is caused by poor hygiene." No, and this belief does the most damage. It starts in the hair follicle and is driven by the immune system. Washing more does not prevent it; washing harder makes inflamed skin worse.
- "They are just boils." A boil is a one-off infection of one follicle that clears and does not return. These recur in the same folds, form tunnels, and are driven by inflammation, not infection. That changes the whole treatment plan.
- "It is a staph infection." Swabs frequently grow nothing, or ordinary skin bacteria. Antibiotics help mostly through their anti-inflammatory effect, which is why they run for months, not the week you would use for an infection.
- "It is contagious." It cannot be passed to a partner, a family member or anyone sharing a towel or pool, and it is not a sexually transmitted infection.
- "Antibiotics will cure it." They control it while you take them, and it returns when you stop. Nothing cures it, though tunnels removed surgically are gone for good.
- "Just lose weight and it will clear." Weight loss reduces severity and is worth doing, but plenty with this condition are not overweight, and being told it is a weight problem is why many stop seeking care.
- "Deodorant causes it." No good evidence. Fragranced products sting inflamed skin, so fragrance-free is more comfortable, but stopping deodorant does not stop the condition.
- "Nothing can be done." That was closer to true twenty years ago. Between hormonal treatment, biologics and small procedures most people improve substantially. The gap between what is possible and what is offered is the real problem.
Questions Patients Ask
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Is this contagious?
No. It cannot be passed through skin contact, towels, swimming pools or sex. It starts in your own hair follicles and is driven by your own immune system.
Why do antibiotics stop working?
They were never killing an infection. Tetracyclines are given for months here because they calm inflammation, and the effect fades when they stop. If antibiotics are not holding, move up to hormonal treatment or a biologic.
Will I need surgery?
Only if tunnels have formed, and not everyone reaches that stage. Medication treats inflammation but cannot close a tunnel, so once one exists a small procedure called deroofing is often the cleanest answer. It is done under local anesthetic and the tunnel does not return.
Does losing weight fix it?
It helps, and it does not fix it. Losing weight reduces friction, reduces affected folds and lowers background inflammation, and many notice fewer flares. But people of every size get this, and treating it as a weight problem is one reason people are sent away without proper treatment.
Can I still shave or have laser hair removal?
Shaving and waxing tend to provoke flares, so clipping is better day to day. Laser hair removal often reduces flares by removing the follicle and is worth considering, particularly in early disease. On deeper skin tones the device matters — ask which laser will be used.
Will it affect having children?
The condition does not affect fertility, but several treatments are not suitable in pregnancy, including some antibiotics and hormonal treatments. Many find it flares in pregnancy and improves afterwards, or the reverse. Plan ahead with the doctor managing your pregnancy, and never start or stop a medicine on your own.
References
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- Zouboulis CC, Bechara FG, Benhadou F, et al. European S2k guidelines for hidradenitis suppurativa/acne inversa part 2: Treatment. Journal of the European Academy of Dermatology and Venereology : JEADV. 2025. — Journal of the European Academy of Dermatology and Venereology : JEADV, 2025
- Alikhan A, Sayed C, Alavi A, et al. North American clinical management guidelines for hidradenitis suppurativa: A publication from the United States and Canadian Hidradenitis Suppurativa Foundations: Part II: Topical, intralesional, and systemic medical management. Journal of the American Academy of Dermatology. 2019. — Journal of the American Academy of Dermatology, 2019
- Jfri A, Nassim D, O'Brien E, et al. Prevalence of Hidradenitis Suppurativa: A Systematic Review and Meta-regression Analysis. JAMA dermatology. 2021. — JAMA dermatology, 2021
- Garg A, Cohn E, Midgette B, et al. Efficacy and Safety of Medical Interventions for Moderate to Severe Hidradenitis Suppurativa: A Living Systematic Review and Network Meta-Analysis. JAMA dermatology. 2025. — JAMA dermatology, 2025
- Calabrese L, Cartocci A, Rubegni P, et al. Efficacy and safety of biologics for hidradenitis suppurativa: A network meta-analysis of phase III trials. Journal of the European Academy of Dermatology and Venereology : JEADV. 2026. — Journal of the European Academy of Dermatology and Venereology : JEADV, 2026
- Shipman WD, Williams MN, Suozzi KC, et al. Efficacy of laser hair removal in hidradenitis suppurativa: A systematic review and meta-analysis. Lasers in surgery and medicine. 2024. — Lasers in surgery and medicine, 2024
