PRODUCT REVIEW

Naturium Multi-Peptide Moisturizer

A well-priced peptide moisturizer from a brand whose co-founder promoted it on YouTube before disclosing she owned it.

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Key facts

Naturium Multi-Peptide Moisturizer at a glance.

Peptide blend

Key active

Lightweight cream

Texture

Everyday moisturizing with a peptide claim

Best for

$20 for 1.7 oz

Approximate price

Fragrance free

Fragrance

1.7 oz

Size

$20.00

Price

Moisturizer

Type

What is it?

Top things to know about Naturium Multi-Peptide Moisturizer

  1. Naturium Multi-Peptide Moisturizer is a lightweight, fragrance-free cream, 1.7 oz for around $20. It is an everyday moisturizer with a peptide claim attached, not a treatment. There are no ceramides in it, despite what several secondhand write-ups say.
  2. The base does the work. Glycerin pulls water into the outer layer, jojoba seed oil and squalane sit on the surface and slow that water leaving, and dimethicone gives it slip. Niacinamide, with better evidence than anything else in the tube, sits eighth. Three peptides follow mid-list, with a vitamin C derivative behind them.
Mixed

Naturium Multi-Peptide Moisturizer is a comfortable, fragrance-free daily cream, and the base is what earns it — glycerin, jojoba and squalane, with niacinamide above the peptides. There are no ceramides in it, whatever secondhand write-ups say. Judge it as a moisturizer; for lines, retinoids are far better evidenced.

— Dr. Schwarz

Skin fit

Is it right for your skin?

Good fit

Normal Skin

A daily moisturizer for the face, light enough for the morning and enough for most people at night. You do not need a skin concern to use it, and at around $20 it is easy to make it the everyday one.

Good fit

Oily Skin

Oily skin still loses water through the surface, which is a separate problem from making too much oil. This cream is light and sinks in without a cushion, so it covers the water side without adding weight. Niacinamide, eighth on the list, is the one ingredient here with good evidence for oil and pore appearance.

Good fit

Sensitive Skin

It is fragrance-free, which removes the most common contact allergen in skincare, and nothing else in it is a common stinger. If you cannot handle a retinoid, a peptide moisturizer is a gentle place to sit.

Texture

What it feels like on skin.

Cream

A light cream that spreads thin and sinks in within a minute, leaving an almost matte finish. Jojoba seed oil is fourth and does real emollient work, but dimethicone and boron nitride keep it from feeling greasy. It sits under makeup and sunscreen without pilling. It is fragrance-free, and 1.7 oz is a face-sized amount rather than something for the body.

Alternatives

If this isn’t the right product for you

Recommended equally

Olay Regenerist Collagen Peptide 24 Moisturizer

Similar price, also fragrance-free, with niacinamide third. There is no collagen in it, despite the name.

Recommended equally

Naturium Multi-Peptide Serum

Same brand, richer at $20 to $25, with peptides ahead of the preservatives. Better for dry skin.

Recommended less

Drunk Elephant Protini Polypeptide Cream

Pleasant, but $68 for 50 ml, and recalled in 2024 for bacterial contamination.

Ingredients · Interactive

What’s in it, and where each ingredient works.

Full ingredient list · 48 ingredients, in label order. Click one.

Simmondsia Chinensis Seed OilSqualaneGlyceryl StearateNiacinamideStearyl AlcoholPalmitoyl Tripeptide-5PantolactonePalmitoyl Tripeptide-1Palmitoyl Tetrapeptide-7Hydrolyzed Plukenetia Volubilis Seed ExtractDunaliella Salina Extract3-O-Ethyl Ascorbic AcidPanthenolCaryodendron Orinocense Seed OilHonokiolMagnololPalmitic AcidSorbitan OleateAluminum Starch OctenylsuccinateHydroxyacetophenoneStearic AcidAcrylamide/Sodium Acryloyldimethyltaurate CopolymerPolyglyceryl-6 Laurate1,2-HexanediolBoron NitrideCaprylyl GlycolPolyglyceryl-10 OleateIsohexadecaneButylene GlycolChlorphenesinAcrylates/C10-30 Alkyl Acrylate CrosspolymerTocopheryl AcetatePolysorbate 80Sorbitan PalmitateSodium HydroxideSodium BenzoateSodium LactatePolysorbate 20Citric AcidPotassium Sorbate
Holds waterSeals and softensKeeps the product working

  1. The base the other ingredients are dissolved in. Most of it evaporates soon after the product goes on.

  2. A small humectant. It moves into the outer layer of skin and holds water there.

  3. A silicone that smooths the surface and adds to the protective film.

  4. Another fatty alcohol. It softens skin and gives the product body.

  5. A form of hyaluronic acid. Its molecule is large, so it stays on the surface and holds water there.

  6. A thickener that gives the product its texture.

  7. The preservative. It stops bacteria and mold from growing in the product.

  8. Helps the preservative work and softens the feel of the product.

What it does
Where it worksSurface
SurfaceBarrierEpidermisDermis

How to use it

How to use it.

Every day

How to apply it

  1. How muchA pea-sized amount for the face. It is light, so it spreads further than it looks.
In a routine

What to pair it with

  1. LayeringAfter your serums, before sunscreen in the morning. At night it is the last step, light enough to buffer a retinoid.
Over time

What to expect

  1. What to expectComfort from the first use. Niacinamide takes four to eight weeks to show on oil and pore appearance. Do not expect the peptides to change lines on a timescale you can measure.

Questions

Common questions.

Is Naturium Multi-Peptide Moisturizer fragrance-free?

Yes.

Does Naturium Multi-Peptide Moisturizer contain ceramides?

No. Despite some write-ups, there are none on the ingredient list.

Is Naturium Multi-Peptide Moisturizer good value?

Yes. Around $20 for 1.7 oz is fair for a competent base.

Do the peptides in Naturium Multi-Peptide Moisturizer work?

Peptides are gentle but modestly proven. A cheap peptide cream and an expensive one rest on the same thin evidence.

What is the brand backstory behind Naturium Multi-Peptide Moisturizer?

A co-founder promoted it on YouTube in the third person before disclosing she owned the brand. No enforcement action followed.

References

Sources.

  1. 1. Oral and topical peptides for skin aging: systematic review and meta-analysis of randomized controlled trials (https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2026.1618306/full) — A 2026 systematic review pooled 19 randomized peptide trials of which only 2 tested topical peptides, and found the wrinkle-reduction benefit was driven almost entirely by oral collagen/polypeptide supplements. Link
  2. 2. Enhanced Skin Permeation of Anti-wrinkle Peptides via Molecular Modification (https://www.nature.com/articles/s41598-017-18454-z) — Backs the claim that peptides are large molecules: the stratum corneum restricts delivery of high-molecular-weight, hydrophilic/charged peptides, so anti-wrinkle peptides like Argireline (889 Da) tend to stay on the skin surface. Link
  3. 3. Naturium Multi-Peptide Moisturizer - 1.7 oz / Ulta Beauty (https://www.ulta.com/p/multi-peptide-moisturizer-pimprod2045652?sku=2627353) — Confirms the product is about $20 for 1.7 oz, is fragrance-free, and lists jojoba (Simmondsia Chinensis) seed oil among its ingredients. Link
  4. 4. Multi-Peptide Moisturizer / Naturium (https://naturium.com/products/multi-peptide-moisturizer-jumbo) — Manufacturer page confirms the moisturizer is fragrance-free, contains Simmondsia Chinensis (Jojoba) Seed Oil, and is built on a peptide blend (Palmitoyl Tripeptide-5/-1, Palmitoyl Tetrapeptide-7). Link