Conditions › PsoriasisBuilt from Airtable · 15 sections
  • Condition
  • Immune-mediated · Chronic

Psoriasis

An overactive immune system tells skin cells to grow many times faster than normal — building raised, scaly plaques that come and go.

Key Facts

Psoriasis at a glance.

2–3%

of people worldwide live with psoriasis — about 125 million people.

3–5 days

for a skin cell to reach the surface in a plaque, versus about 28 days normally.

1 in 3

people with psoriasis develop psoriatic arthritis.

0%

contagious. You can’t catch it or spread it by touch.

What Is It?

An immune condition that shows up on the skin.

Psoriasis is a long-term inflammatory disease. Immune cells send the wrong signals, and skin cells respond by multiplying far too quickly. The extra cells pile up into thick, scaly patches called plaques.

It usually flares and settles in cycles. It can start at any age, but most often appears between 15–35 or 50–60.

At a glance

Chronic

Lifelong, with flares and calmer periods.

Immune-driven

T cells and IL-17, IL-23 and TNF signals.

Systemic

Linked to joint, heart and metabolic health.

Very treatable

Modern options clear most people’s skin.

Symptoms

What it looks and feels like.

Raised, well-defined plaques

Thick patches with sharp edges, often on both sides of the body.

Silvery-white or gray scale

Flakes that lift off, sometimes leaving tiny bleeding points.

Itch, burning or soreness

Most people itch, and plaques can sting or feel tight.

Cracked, dry skin

Plaques over joints may split and bleed.

Nail changes

Pitting, yellow-brown “oil drop” spots, lifting.

Joint pain or stiffness

Morning stiffness or swollen fingers — tell your doctor.

Subtypes

Five main types.

Most people have one main type, but types can overlap or change over time.

Plaque

80–90% of cases. Thick, scaly plaques.

Guttate

~8% Small drop-like spots, often after strep throat.

Inverse

3–7% Smooth, shiny patches in skin folds — little scale.

Pustular

~3% Rare. Pus-filled bumps on palms, soles or widespread.

Erythrodermic

1–2% Rare and urgent. Red, peeling skin over most of the body.

Important. Seek care the same day if redness covers most of your body, or you have widespread pustules with fever, chills or feeling unwell.

Across Skin Tones

Not always red. Not always silver.

On darker skin, psoriasis often looks violet, gray or dark brown, and it is more likely to leave lasting dark or light marks after it heals.

Light

Pink to red plaques with silvery-white scale.

Medium

Salmon to red-brown with silvery-white scale.

Brown

Violet to purple-brown with gray scale.

Deep

Dark brown or purple; marks may linger for months.

Swatches are illustrations until the four clinical photos are added.

Causes & Risk Factors

Genes load the gun. Triggers pull it.

Three things work together

About 1 in 3 people with psoriasis has a close relative with it. Gene variants such as HLA-C*06:02 raise the risk.

Things that raise your risk

  • Family historyStrong link
  • SmokingStrong link
  • ObesityStrong link
  • Heavy alcohol useModerate
  • Strep and other infectionsModerate
  • Lithium, beta-blockers, antimalarialsSome people

What's Happening in the Skin · Interactive

From one signal to a plaque.

Step through what happens beneath a psoriasis plaque — and where each kind of treatment steps in.

  1. New skin cells form at the base of the epidermis and take about 28 days to rise, flatten and shed.

    Normal cycle: about 4 weeks

  2. In people with an inherited tendency, strep throat, stress or a skin injury wakes up immune “alarm” cells in the dermis.

    Avoiding your triggers lowers flare risk

  3. Alarm cells release IL-23, which drives T cells to pour out IL-17 and TNF. These signals tell skin cells to multiply.

    Biologics block IL-17, IL-23 or TNF here

  4. Skin cells divide so fast they reach the surface in 3–5 days instead of about 28. The epidermis thickens.

    Vitamin D creams slow this turnover

  5. Immature cells pile up as silvery scale, and widened blood vessels make the patch red and raised.

    Steroids calm it; salicylic acid lifts scale

Triggers & Aggravating Factors

Know what sets off a flare.

Triggers differ from person to person. A simple flare diary for 2–3 months is the best way to find yours.

Can start a flare

  • Stress
  • Strep throat
  • Skin injury, cuts, tattoos
  • Sunburn
  • Stopping oral steroids
  • Certain medications

New plaques that form along a scratch or wound are called the Koebner phenomenon.

Can make it worse

  • Cold, dry weather
  • Smoking
  • Heavy drinking
  • Weight gain
  • Scratching, picking
  • Hot showers

Losing weight, if you carry extra weight, can improve psoriasis and help treatments work better.

Daily Care & Prevention

Small habits, calmer skin.

Morning

AM
  1. 1Short, lukewarm shower. Under 10 minutes; pat dry.
  2. 2Moisturize within 3 minutes. Fragrance-free cream or ointment.
  3. 3Apply treatment. As prescribed, on plaques only.
  4. 4Sunscreen. On exposed skin, SPF 30+.

Evening

PM
  1. 1Soften scale. Salicylic acid or urea cream on thick patches.
  2. 2Apply treatment. As prescribed.
  3. 3Seal it in. A thick ointment such as petrolatum.
  4. 4Scalp? Medicated shampoo 2–3× a week; leave on 5 min.

Don’t pick scale

It can trigger new plaques.

Quit smoking

Linked to more severe disease.

Limit alcohol

Flares and treatment safety.

Manage stress

A common flare trigger.

Treatments

A treatment for every level.

Doctors usually start with creams for limited psoriasis and move to light, pills or injections when it covers more skin, affects the joints, or doesn’t respond.

Mild · limited skinModerate to severe · widespread or joints

Over-the-counter

Salicylic acid 2–3%

Moderate

Softens and lifts scale so other treatments can get in.

Coal tar

Moderate

Slows skin cell growth; shampoos, creams and bath solutions.

Hydrocortisone 1%

Limited

Mild steroid; helps itch on thin skin, rarely enough alone.

Thick moisturizers

Moderate

Ointments and urea creams reduce dryness and cracking.

Outlook

Lifelong, but very manageable.

There’s no cure yet, but most people reach clear or almost-clear skin with the right plan. Expect periods of flares and quieter stretches.

  1. 1

    Diagnosis

    Usually by examining skin, scalp and nails. A biopsy is rarely needed.

  2. 2

    2–8 weeks

    Creams and ointments usually show clear improvement.

  3. 3

    12–16 weeks

    Typical check-in point for pills, light therapy and biologics.

  4. 4

    Long term

    Maintenance keeps flares rare; plans are adjusted over time.

Complications

More than skin deep.

The same inflammation can affect other parts of the body. Treating psoriasis well may lower some of these risks.

Psoriatic arthritis

Up to 30% of people. Joint pain, swelling, heel pain, “sausage” fingers. Early treatment prevents damage.

Heart disease

Higher risk of heart attack and stroke, especially with severe psoriasis.

Metabolic syndrome

Higher rates of type 2 diabetes, high blood pressure, high cholesterol and fatty liver.

Depression & anxiety

Common, and worth raising with your doctor. Support helps.

Inflammatory bowel disease

Crohn’s disease and ulcerative colitis are more common.

Eye inflammation

Uveitis — a painful red eye or blurry vision needs prompt care.

Lookalikes

Is it psoriasis — or something else?

Itchier, blurrier edges, often in elbow and knee creases rather than on the outside.

Seborrheic dermatitis

Greasy, yellowish flakes on the scalp, eyebrows and sides of the nose.

Ringworm (tinea)

A ring with a clearer center that slowly spreads outward. A skin scraping confirms it.

Pityriasis rosea

Starts with one larger “herald” patch, then oval spots; fades in 6–8 weeks.

Common Questions

What patients ask us.

Is psoriasis contagious?

No. You can’t catch psoriasis from touching someone, sharing towels or swimming together.

Can psoriasis be cured?

Not yet. But many people reach clear or almost-clear skin and stay that way with ongoing treatment.

Does diet make a difference?

No single diet cures psoriasis. Losing extra weight and limiting alcohol can reduce severity and help treatments work.

Is it hereditary?

Genes play a big role — about a third of people have a family member with psoriasis — but not everyone with the genes gets it.

Are biologics safe?

For most people, yes. They slightly raise infection risk, so you’ll be screened for TB and hepatitis first and monitored over time.

When should I see a dermatologist?

If over-the-counter care hasn’t helped in a few weeks, it’s spreading, it affects your nails or scalp, or your joints ache.

References

  1. Armstrong AW, Read C. Pathophysiology, clinical presentation, and treatment of psoriasis: a review. JAMA. 2020;323(19):1945–1960.
  2. Griffiths CEM, Armstrong AW, Gudjonsson JE, Barker JNWN. Psoriasis. Lancet. 2021;397(10281):1301–1315.
  3. Menter A, et al. Joint AAD–NPF guidelines of care for the management and treatment of psoriasis with biologics. J Am Acad Dermatol. 2019;80(4):1029–1072.
  4. Elmets CA, et al. Joint AAD–NPF guidelines of care for the management and treatment of psoriasis with phototherapy. J Am Acad Dermatol. 2019;81(3):775–804.
  5. Kaufman BP, Alexis AF. Psoriasis in skin of color: insights into the epidemiology, clinical presentation, genetics, quality-of-life impact, and treatment. Am J Clin Dermatol. 2018;19(3):405–423.

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