Revofil
No US approval Revofil comes from a South Korean company. Nothing sold under the name has been reviewed for use here. So what is in the syringe cannot be checked against any US record.
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Dermapedia / CompareProcedures
Revofil vs Juvederm
Juvederm is FDA-approved. Revofil is not. Juvederm is a family of seven hyaluronic acid gels, and each one is approved for a named part of the face. Revofil has no US approval, so there is no US record of what is in the syringe. That gap is the whole comparison.
At a glance
| The difference | Revofil | Juvederm |
|---|---|---|
| What it is | No US approval | Seven hyaluronic acid gels |
Juvederm
Side by side
The differences that matter
What it is
Revofil
No US approval
Revofil comes from a South Korean company. Nothing sold under the name has been reviewed for use here. So what is in the syringe cannot be checked against any US record.
Juvederm
Seven hyaluronic acid gels
Each of the seven is a different gel. Each has its own named use and its own trial.
Where it can be used
Revofil
No named use
There is no US indication for it.
Juvederm
Named areas, product by product
Folds, lips, lines around the mouth, cheeks, chin, temples, jawline, under-eye hollows, and the smoothness of cheek and neck skin. Each area belongs to one specific product, not to the brand.
How long it lasts
Revofil
Not published
For every approved filler, FDA publishes a summary of how well it works and how safe it is. There is none for Revofil.
Juvederm
6 to 24 months, depending on the product
Voluma XC, for example, was followed to 24 months.
How it reaches a clinic
Revofil
Through online resellers
FDA tells the public not to buy dermal fillers sold straight to consumers. Products sold that way "may be fake, contaminated, or not approved for use in the U.S."
Juvederm
Prescription-only, through a provider
Approved dermal fillers are for prescription use only. They are supplied to licensed health care providers.
If something goes wrong
Revofil
No record of what was injected
It carries the same risks as any filler. But there is no verified record of the material. In one hospital series of 31 people treated for filler problems, over half the products were uncertified or of unknown origin. The most common problems were biofilm and long-running immune reactions.
Juvederm
Hyaluronic acid, so it can be dissolved
An enzyme called hyaluronidase breaks it down. That use is off-label in the US. Juvederm gels were among the most resistant in one lab comparison, needing 300 units to break down within an hour.
The at-home or drugstore version
Revofil
No home version
A filler bought from a reseller has no verified contents. It has no approved labeling telling anyone where or how deep to place it, and nobody is accountable for the result.
Juvederm
No home version
Lip plumpers work by mildly irritating the lip, so it swells for a few hours. Hyaluronic acid creams sit on the surface of the skin. Neither one places a gel under the skin, which is the whole of what a filler does.
Who tends to be happy with it
Revofil
- Best for — No one in the US. There is no way to verify what is in the syringe.
- The mindset — Ask for the product name, the maker and the approval number, and expect a straight answer.
Juvederm
- Best for — Someone who wants a filler approved for the exact area being treated.
- The mindset — Ask which product, for which area, and what its own trial measured.
What "no FDA approval" actually means
Revofil
It does not mean FDA looked at Revofil and rejected it. It means no approval application appears in the record at all.
The fine print
Revofil
Revofil is a Caregen product. No record exists under that name in the FDA device approval database.
Juvederm
Juvederm's seven products, from Allergan Aesthetics, sit under two premarket approvals: one application from 2006 covering the Ultra line, and one from 2013 covering the rest. Each individual product was added by a supplement that FDA reviewed separately. Follow-up ran to 24 months for Voluma XC, 18 months for Vollure XC, 12 months for Volux XC, 12 months in lips and 24 weeks in folds for Ultra XC, and 6 months for Skinvive.
More photographs
Juvederm
Compare the total cost
Revofil
Before comparing price, ask the clinician to identify the exact Revofil product and its regulatory status where you live. Then ask how much product the proposed treatment uses.
Juvederm
Ask which Juvederm product, how many syringes, and which treatment area the quote covers. Include the policy and price for a touch-up.
Common questions
Questions Patients Ask
Is Revofil FDA-approved?
No. There is no record for Revofil in the FDA's device approval database. Dermal fillers are Class III devices that require premarket approval, and there is no lesser route a filler could take instead, so the absence of a record means the product has no legal route to the US market.
Is it legal to inject Revofil in the United States?
An unapproved Class III device cannot legally be marketed in the US. This is different from off-label use, where an approved product is used in an area it was not approved for — that is legal and routine. Revofil is not an approved product being used off-label; it has no US approval at all.
How long does Revofil last?
There is no answer that can be checked. FDA publishes a summary of safety and effectiveness data for every approved filler, including its trial design and follow-up length. No such document exists for Revofil, so any duration figure attached to it is not traceable to a regulatory record.
Where does Revofil sold in the US come from?
Products under this name are associated with Caregen, a South Korean company, and reach US buyers through online resellers rather than an approved supply chain. FDA advises the public not to buy dermal fillers sold directly to consumers, and states that products sold that way may be fake, contaminated, or not approved for use in the US.
What should I ask a clinic that offers it?
Ask for the product name and manufacturer, whether it is FDA-approved, the approval number, and what facial area that approval covers. A clinic using an approved product can answer all four. FDA's own guidance tells patients to know the product being injected and to read its patient labeling.
I have already had Revofil. What now?
See a licensed dermatologist or plastic surgeon and tell them exactly what you had and when. Bring the packaging if you still have it. If the material was hyaluronic acid, hyaluronidase may be an option, though that use is off-label in the US. If nobody can establish what was injected, nobody can say whether it can be dissolved.
Is Juvederm one product?
No. Juvederm is seven products under two FDA approvals: Ultra XC, Ultra Plus XC, Voluma XC, Vollure XC, Volbella XC, Volux XC and Skinvive. Each has its own approved area and its own trial. Ultra XC is approved for lips, for example, and Ultra Plus XC is not.
Does an approval mean a filler is risk-free?
No. Every filler, approved or not, carries the risk of the material entering a blood vessel, which can cause skin loss or vision loss. Approval means the product's evidence and labeling were reviewed for a named use, and that an injector has instructions on where and how deep to place it. It does not remove the risk.
Safety to keep in mind
A filler cannot be sold here just because it resembles an existing product. It needs its own clinical evidence for its own named use. That is why the approved products name such specific areas — cheeks, chin, temples, jawline — rather than the face in general.
Three things follow. There is no FDA-reviewed evidence that the product works. There is no FDA-reviewed evidence about its safety. And there is no approved labeling telling an injector where and how deep to place it.
You are entitled to see what is being put in your face. FDA tells patients to know the type of product being injected, and to ask for the patient labeling that comes with approved fillers.
Four questions get you the answer. What is the product's name and maker? Is it FDA-approved? Which approval number? What area is that approval for? A clinic using an approved product will answer all four without hesitation.
If the answer to the second question is no, ask why. Approved options exist for nearly every part of the face, so there is a reason another product is being used, and you should hear it.