Juvederm
Juvederm is a hyaluronic acid filler. It is placed with a needle or a blunt cannula.
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Juvederm vs Rejuran
Juvéderm is for volume you can point at. It is a hyaluronic acid gel that fills a lip, a cheek or a fold on the day, lasts roughly a year, and can be dissolved if you change your mind. Rejuran is for the surface of the skin. It uses polynucleotides, fragments of salmon DNA, to improve texture and fine lines across three visits, and it adds no volume at all. They fix different complaints, so the choice is usually easy once you name yours.
At a glance
| The difference | Juvederm | Rejuran |
|---|---|---|
| What is in the syringe | Hyaluronic acid gel | Polynucleotides from salmon DNA |
| When you see the result | The same day | Two to four weeks, building for three months |
| What it feels like | A few injections, numbed | Many small pinpricks |
| Cost | Priced per syringe | Priced per session, and you need three |
Rejuran
Rejuran is injected in small amounts across the area. It is usually done as a series of visits.
Side by side
The differences that matter
What is in the syringe
Juvederm
Hyaluronic acid gel
Hyaluronic acid is a sugar your skin already makes. The gel holds a space open.
Rejuran
Polynucleotides from salmon DNA
Purified DNA fragments. Not a filler, and no volume.
What it improves
Juvederm
Shape and volume
Thin lips, flat cheeks, a weak chin, a deep fold beside the nose. It changes the outline of your face.
Rejuran
Texture and repair
Rough texture, fine lines, shallow acne scars, large pores and skin that reacts to everything.
What it will not do
Juvederm
It will not smooth rough skin
A filled cheek can still look dull and uneven on the surface.
Rejuran
It will not fill a hollow
A flat cheek stays flat. A thin lip stays thin.
When you see the result
Juvederm
The same day
Swelling settles over about two weeks and the look settles with it.
Rejuran
Two to four weeks, building for three months
Nothing changes on the day. Texture improves first, then fine lines.
How many visits
Juvederm
Usually one
A top-up later if you want more.
Rejuran
Usually three
Spaced three to four weeks apart, then one session every six to twelve months.
How long it lasts
Juvederm
Roughly a year
Longer in the cheek, shorter in the lips, because the lips move constantly.
Rejuran
Six to twelve months
It is a maintenance treatment. Skin drifts back if you stop.
Can it be undone
Juvederm
Yes
Hyaluronidase dissolves it, usually within a day or two.
Rejuran
Nothing to remove
There is no material left sitting there, so there is nothing to dissolve. It simply wears off.
What it feels like
Juvederm
A few injections, numbed
Most Juvéderm products contain a numbing agent already.
Rejuran
Many small pinpricks
Spread across the whole area, so it takes longer and is the less comfortable of the two. Small bumps flatten within a day or two.
Side effects to expect
Juvederm
Bruising, swelling, tenderness
Lumps and unevenness happen, and they can be dissolved.
Rejuran
Bruising, swelling, small bumps
Marks at each injection point for a day or two. Plan a few clear days.
Cost
Juvederm
Priced per syringe
Easy to total up front. Repeat visits add up over the years.
Rejuran
Priced per session, and you need three
Ask for the cost of the full course rather than one visit.
The at-home or drugstore version
Juvederm
A hyaluronic acid serum
A serum holds water in the top layer for a few hours. Filler goes millimetres down.
Rejuran
Salmon DNA creams are a different thing
Topical products with these ingredients exist and feel pleasant. Injected polynucleotides are placed inside the skin, which a cream cannot do.
Who each suits
Juvederm
- Best for — One feature you can point at in the mirror.
- The mindset — You want the change today, with a way out.
Rejuran
- Best for — Rough, thin, marked or easily irritated skin.
- The mindset — You will do three visits and wait for the change.
They are not really competitors
Rejuran
Rejuran changes the surface of your skin. It is spread through the skin itself, a few millimetres down, and the aim is a smoother, less fragile surface. Nobody sees a change in shape.
Reversibility is worth understanding here
Rejuran
Rejuran has nothing to take out. No gel is left sitting in the tissue, so a result you dislike simply fades. That is not the same as being reversible, but it does mean there is no lump to remove.
Where these are used
Rejuran
Rejuran is not approved in the United States for these uses. It is widely used in Korea and in several other countries. Some US clinics offer it anyway. It is fair to ask a clinic what they use and where it comes from.
Has anyone compared them directly
Rejuran
No trial has put Juvéderm against Rejuran. They are measured on different things, so a fair comparison would struggle to pick a single yardstick. Any claim that one beats the other comes from clinic experience.
Common questions
Questions Patients Ask
Is Rejuran a filler?
No. Rejuran adds no volume. It is a skin booster made from polynucleotides, which are fragments of salmon DNA, and it works on the texture and quality of the skin.
Should I get Juvederm or Rejuran?
If you can point at a hollow, a thin lip or a fold, Juvéderm is the treatment that addresses it. If your complaint is rough, thin or marked skin, Rejuran is the better fit.
Can I have both?
Yes, and many people do, at separate visits. One works on shape and the other on the surface, so they do not overlap.
Is Rejuran available in the United States?
It is not approved in the United States for these uses. It is widely used in Korea and several other countries, and some US clinics offer it anyway.
Which one hurts more?
Rejuran involves many small injections spread across the area, so it usually takes longer and is less comfortable. Most Juvéderm products contain a numbing agent already.
How long does each last?
Juvéderm lasts roughly a year, longer in the cheek and shorter in the lips. Rejuran lasts six to twelve months and is repeated as maintenance.