BioRePeel
BioRePeel is dispensed from a syringe and spread over the face, then massaged in. It is not injected.
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Dermapedia / CompareProcedures
Biorepeel vs VI Peel
BioRePeel is sold as a peel you do not peel from. It is an Italian product, put on and taken off in the clinic in a few minutes. The VI Peel is sold on the peeling. It is a US solution you leave on and wash off at home, and no trial has ever compared the two.
At a glance
| The difference | BioRePeel | VI Peel |
|---|---|---|
| What is actually in it | TCA, strength undisclosed | Acids plus phenol, strengths undisclosed |
| Sessions and cost | No published course length | 3 to 6 peels, 4 to 6 weeks apart |
VI Peel
A VI peel leaves a yellow tint on the skin while it works. Peeling usually starts a few days later.
Side by side
The differences that matter
What you actually do
BioRePeel
Applied and removed in the clinic
Your provider applies it and wipes it off in the same visit. The maker sells it as an exfoliating serum, not a classic peel.
VI Peel
Applied in clinic, washed off at home
The solution stays on your skin. You wash it off yourself after the time your provider gives you. Nothing else goes on your face for four hours. There are five variants.
What is actually in it
BioRePeel
TCA, strength undisclosed
Trichloroacetic acid is a standard peeling acid. Here it sits in a two-phase oil-and-water system. The official site gives no acid concentration.
VI Peel
Acids plus phenol, strengths undisclosed
The maker lists five things, with no percentages. They are trichloroacetic acid, phenol, retinoic acid, salicylic acid and vitamin C. Precision Plus adds hydroquinone and kojic acid for pigment. Purify adds benzoyl peroxide and hydrocortisone for acne. Phenol is the classic deep-peel agent, so it is worth noting.
How deep it goes
BioRePeel
Sold as working without wounding skin
Depth depends on the acid, its strength and the number of coats. With no published strength, nobody outside the company can place it on a depth scale.
VI Peel
Sold as medium depth
Published charts call trichloroacetic acid at 35 to 50 percent a medium peel. Above 50 percent counts as deep. The strength used here is not published, so it cannot be placed on that scale either.
Whether you visibly peel
BioRePeel
Sold as no visible shedding
That is the product's main selling point, and it is an unmeasured one. No published study has recorded how much skin sheds after it, or whether any does.
VI Peel
Flaking from day three, for 3 to 4 days
That is the maker's instruction, not published data, and it varies from person to person. Healing after a true medium-depth peel takes longer: 7 to 10 days.
What the evidence shows
BioRePeel
Nothing published
No study of BioRePeel has ever been published. Everything claimed for it rests on the maker's own material.
VI Peel
One paper, not a controlled trial
One 2024 paper of 30 people, with no control group. Everyone got a VI Peel and Botox the same day, to check that doing both together was safe.
Sessions and cost
BioRePeel
No published course length
The maker publishes no number of sessions and no interval. The clinic sets the course you are quoted.
VI Peel
3 to 6 peels, 4 to 6 weeks apart
Then about 4 a year to keep it up. That is a maker's protocol, not a tested schedule.
Who tends to be happy with it
BioRePeel
- Best for — Someone who wants a short treatment with no flaking to plan around, and who is comfortable that the claims have not been tested.
- Ask before you book — Which product exactly, and where it was bought.
- The mindset — Treat it as maintenance, not a correction.
VI Peel
- Best for — Someone who has a week to give to peeling, and who wants the variant matched to a problem such as pigment or acne.
- Ask before you book — Which variant, and why that one for your skin.
- The mindset — Plan the week. Peeling starts around day three.
Darker skin tones
VI Peel
VI Peel says all of its treatments are safe for all skin tones. That claim has not been tested in a trial. Its one published study did cover the full range of skin tones, but it was not built to measure pigment safety.
The fine print
BioRePeel
BioRePeel does not appear in FDA's device registration and listing database at all. In Europe it carries a CE mark as a medical device, a separate route in which a notified body assesses the maker's documentation. FDA does not recognise CE marking, so a clinic page calling BioRePeel "FDA approved" is incorrect.
Common questions
Questions Patients Ask
Is BioRePeel really a peel you don't peel from?
That is how it is marketed, and it has never been measured. No published study has recorded how much skin sheds after BioRePeel, or whether any does. What clinics say about it comes from the manufacturer. The VI Peel, by contrast, is sold on visible shedding: its maker says peeling usually starts around day three and lasts three to four days.
If I don't peel, is it doing less?
Nobody knows, in either direction. Visible flaking only tells you the surface layer separated and came away. No published work links how much you shed after a peel to the result you end up with. So a product that makes you peel is not automatically doing more, and one that does not is not automatically doing less. "No downtime" is a claim about your calendar, not about depth or safety.
Is BioRePeel FDA approved?
No, and this is the most common error on pages about it. No chemical peel product of any kind is FDA approved — FDA stated on 30 July 2024 that it "has not approved any chemical peel products." BioRePeel is not FDA cleared either, and it does not even appear in FDA's device registration and listing database. It is CE-marked in Europe, which is a separate European process; FDA does not recognize CE marking, and "FDA registered" is not an approval status.
Is the VI Peel FDA approved?
No. Neither the VI Peel nor any of its variants has FDA approval or clearance. That is not unusual and does not make it illegal. It means no US authority has reviewed whether it works, and no authority sets a maximum concentration for a professional peel formula before it goes on sale.
Which one is better for pigmentation?
No trial has compared them, so this cannot be answered from evidence. What can be said is that VI Peel sells a variant, Precision Plus, that adds hydroquinone and kojic acid — two established skin-lightening ingredients — specifically for sun damage, melasma and post-inflammatory hyperpigmentation. BioRePeel publishes no pigment-directed formula and no data. If pigment is the reason you are booking, that is a difference worth weighing.
Which costs more?
There is no reliable published price for either. No professional society survey, no government dataset and no manufacturer list price exists for branded peels, so anything quoted is one clinic's menu. For scale, the last separate figure published for a chemical peel of any kind was a national average surgeon fee of $519 in 2020, in a single bucket covering everything from a light glycolic peel to a deep phenol peel and excluding facility fees. The society that published it stopped reporting fees for treatments like this after 2023.
How many sessions will I need?
VI Peel's manufacturer recommends a series of 3 to 6 peels, every 4 to 6 weeks, then about 4 a year for maintenance — that is the maker's protocol, not a trial result. BioRePeel's manufacturer does not publish a course length, so the number you are quoted is set by the clinic. For context, published peel trials most often used 3 to 6 sessions at 2-week intervals, with superficial agents.
Safety to keep in mind
Say when you book if you get cold sores, not on the day. Antiviral medicine has to be started in advance, because a flare happens while the skin heals. In the best published data, 50% of people with a history of cold sores and no antiviral had an outbreak after a peel around the mouth. With aciclovir, 8.3% did.
Tell your provider if you have taken isotretinoin (Accutane) in the last six months. It is a labelled precaution. Expert panels have since said the evidence for delaying light peels is not strong. Treat it as a conversation, not a rule.
Say if you are allergic to aspirin, hydroquinone or phenol. All three are listed as reasons not to have the VI Peel. Also mention immune suppression, autoimmune disease, liver disease, or any open area of skin.
Ask who is applying it and what training they have. Who may legally apply a peel is set state by state. Light peels are within an esthetician's scope in most states. Medium and deep peels are medical almost everywhere.
Plan for sun. Peel acids make skin more sensitive to the sun. FDA's label wording asks for sun protection during use and for a week after.
No chemical peel product is FDA approved. FDA said so on 30 July 2024, adding that peel products should only be used under the supervision of a dermatologist or a licensed and trained practitioner.
Neither product is FDA cleared either. FDA's 510(k) database returns no chemical peel of any kind, and the acids used in peels have no approved drug application.
Neither maker has to publish concentrations. Professional-use products are exempt from the consumer ingredient rules, which is legal and ordinary. The 35% TCA figure that circulates on reseller pages cannot be traced to the maker or to any regulatory filing.